Summary. The article is devoted to the current state and development of scientific - technical progress in Ukraine and in the world, the basic trends and features of the impact on industries. In the article the necessity of large-scale changes that lead technological "breakthrough" in Ukraine.

Keywords: scientific - technical progress, innovation development, innovation.

Summary. The article is devoted to the current state and development of scientific - technical progress in Ukraine and in the world, the basic trends and features of the impact on industries. In the article the necessity of large-scale changes that lead technological "breakthrough" in Ukraine.

Keywords: scientific - technical progress, innovation development, innovation.

Annotations: in the article the problem of the use of program-target approach in managing innovation in the enterprise

Keywords: program - targeted approach, innovation, innovation.

Abstract: The Article is devoted to assessing and promoting introduction of achievements of scientific and technical progress in activity of enterprises in modern conditions of resource constraints and the depreciation of fixed assets.

Key words: scientific and technical progress, innovative activity, innovations.